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concanavalin a  (Vector Laboratories)


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    Vector Laboratories concanavalin a
    Concanavalin A, supplied by Vector Laboratories, used in various techniques. Bioz Stars score: 93/100, based on 23 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rhodamine+concanavalin+a/pmc12867842-99-26-30?v=Vector+Laboratories
    Average 93 stars, based on 23 article reviews
    concanavalin a - by Bioz Stars, 2026-07
    93/100 stars

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    Fig. 3 Overexpression of CDC20 attenuates DOX-induced cardiac dysfunction, fibrosis, and apoptosis. a Survival curve of mice in each group: b EF% statistics of mice in each group (n = 6–13); c HW/TL statistics of mice in each group (n = 6–13); d Representative image of Masson staining in each group (n = 6–13, bar = 100 μm); e Representative image and statistics of WGA staining in each group (n = 6–13, bar = 50 μm); f HE staining image in each group (n = 6–13, bar = 40 μm); g Representative image and statistical data of vacuolization in each group (n = 6–13, bar = 40 μm); h Representative image and statistical data of TUNEL staining in group (n = 6–13, bar = 40 μm); i Detected expression of Bax, Bcl-2, and β-actin using western blotting (n = 4). DOX: doxorubicin, EF: ejection factor, H&E: Hematoxylin and eosin, HW/TL: heart weight/tibia length, TUNEL: terminal deoxynucleotidyl transferase dUTP nick end labeling, WGA: wheat germ agglutinin. Data presented as mean ± SD. Statistical analysis performed with two-way ANOVA

    Journal: Cellular & molecular biology letters

    Article Title: CDC20 protects the heart from doxorubicin-induced cardiotoxicity by modulating CCDC69 degradation.

    doi: 10.1186/s11658-025-00708-8

    Figure Lengend Snippet: Fig. 3 Overexpression of CDC20 attenuates DOX-induced cardiac dysfunction, fibrosis, and apoptosis. a Survival curve of mice in each group: b EF% statistics of mice in each group (n = 6–13); c HW/TL statistics of mice in each group (n = 6–13); d Representative image of Masson staining in each group (n = 6–13, bar = 100 μm); e Representative image and statistics of WGA staining in each group (n = 6–13, bar = 50 μm); f HE staining image in each group (n = 6–13, bar = 40 μm); g Representative image and statistical data of vacuolization in each group (n = 6–13, bar = 40 μm); h Representative image and statistical data of TUNEL staining in group (n = 6–13, bar = 40 μm); i Detected expression of Bax, Bcl-2, and β-actin using western blotting (n = 4). DOX: doxorubicin, EF: ejection factor, H&E: Hematoxylin and eosin, HW/TL: heart weight/tibia length, TUNEL: terminal deoxynucleotidyl transferase dUTP nick end labeling, WGA: wheat germ agglutinin. Data presented as mean ± SD. Statistical analysis performed with two-way ANOVA

    Article Snippet: The tissue sections were dewaxed and rehydrated, followed by a 60-min incubation with WGA staining (2 ng/ml, VECTOR, RL-1002).

    Techniques: Over Expression, Staining, TUNEL Assay, Expressing, Western Blot

    Fig. 6 Overexpression of CCDC69 intervenes in the protective effect of CDC20 against doxorubicin-induced myocardial injury. a Representative images and statistical data of Masson and collagen III staining in each group (n = 6, bar = 50 μm); b Representative images and statistics data of α-SMA and H&E staining in each group (n = 6, bar = 50 μm); c Representative images and statistical data of WGA staining in each group (n = 6, bar = 20 μm); d Representative images and statistical data of vacuolization in each group (n = 6, bar = 50 μm); e Representative images and statistical data of TUNEL staining in each group (n = 6, bar = 20 μm); f Bax, Bcl-2, and β-actin expression through western blot (n = 4). α-SMA: alpha-smooth muscle actin, H&E: hematoxylin and eosin, TUNEL: terminal deoxynucleotidyl transferase dUTP nick end labelling, WGA: wheat germ agglutinin. Data presented as mean ± SD. Statistical analysis performed with two-way ANOVA

    Journal: Cellular & molecular biology letters

    Article Title: CDC20 protects the heart from doxorubicin-induced cardiotoxicity by modulating CCDC69 degradation.

    doi: 10.1186/s11658-025-00708-8

    Figure Lengend Snippet: Fig. 6 Overexpression of CCDC69 intervenes in the protective effect of CDC20 against doxorubicin-induced myocardial injury. a Representative images and statistical data of Masson and collagen III staining in each group (n = 6, bar = 50 μm); b Representative images and statistics data of α-SMA and H&E staining in each group (n = 6, bar = 50 μm); c Representative images and statistical data of WGA staining in each group (n = 6, bar = 20 μm); d Representative images and statistical data of vacuolization in each group (n = 6, bar = 50 μm); e Representative images and statistical data of TUNEL staining in each group (n = 6, bar = 20 μm); f Bax, Bcl-2, and β-actin expression through western blot (n = 4). α-SMA: alpha-smooth muscle actin, H&E: hematoxylin and eosin, TUNEL: terminal deoxynucleotidyl transferase dUTP nick end labelling, WGA: wheat germ agglutinin. Data presented as mean ± SD. Statistical analysis performed with two-way ANOVA

    Article Snippet: The tissue sections were dewaxed and rehydrated, followed by a 60-min incubation with WGA staining (2 ng/ml, VECTOR, RL-1002).

    Techniques: Over Expression, Staining, TUNEL Assay, Expressing, Western Blot

    Fig. 7 Cardiomyocyte-specific overexpression of CDC20 significantly inhibits DOX-induced myocardial injury, while not affecting the antitumor effect of DOX. a Representative images of HE staining in each group (n = 6, bar = 100 μm); b Representative images and statistical data of vacuolization in each group (n = 6, bar = 50 μm); c Representative images and statistical data of Masson staining in each group (n = 6, bar = 100 μm); d Representative images and statistical data of α-SMA staining in each group (n = 6, bar = 50 μm); e Representative images and statistical data of WGA staining in each group (n = 6, bar = 50 μm); f Tumor growth curves of mice in each group (n = 6); g Representative images of tumor in each group; h Statistical data of tumor volume (n = 6); i Statistical data of tumor weight (n = 6); j Representative images and statistical data of PCNA staining in each group (n = 6, bar = 50 μm); k Bax, PCNA, and β-actin expression through western blot (n = 3); l Caspase-3 activity in each group (n = 3). α-SMA: alpha-smooth muscle actin, H&E: hematoxylin and eosin, HW/TL: heart weight/tibia length, PCNA: proliferating cell nuclear antigen, TUNEL: terminal deoxynucleotidyl transferase dUTP nick end labeling, WGA: wheat germ agglutinin. Data presented as mean ± SD. Statistical analysis performed with two-way ANOVA

    Journal: Cellular & molecular biology letters

    Article Title: CDC20 protects the heart from doxorubicin-induced cardiotoxicity by modulating CCDC69 degradation.

    doi: 10.1186/s11658-025-00708-8

    Figure Lengend Snippet: Fig. 7 Cardiomyocyte-specific overexpression of CDC20 significantly inhibits DOX-induced myocardial injury, while not affecting the antitumor effect of DOX. a Representative images of HE staining in each group (n = 6, bar = 100 μm); b Representative images and statistical data of vacuolization in each group (n = 6, bar = 50 μm); c Representative images and statistical data of Masson staining in each group (n = 6, bar = 100 μm); d Representative images and statistical data of α-SMA staining in each group (n = 6, bar = 50 μm); e Representative images and statistical data of WGA staining in each group (n = 6, bar = 50 μm); f Tumor growth curves of mice in each group (n = 6); g Representative images of tumor in each group; h Statistical data of tumor volume (n = 6); i Statistical data of tumor weight (n = 6); j Representative images and statistical data of PCNA staining in each group (n = 6, bar = 50 μm); k Bax, PCNA, and β-actin expression through western blot (n = 3); l Caspase-3 activity in each group (n = 3). α-SMA: alpha-smooth muscle actin, H&E: hematoxylin and eosin, HW/TL: heart weight/tibia length, PCNA: proliferating cell nuclear antigen, TUNEL: terminal deoxynucleotidyl transferase dUTP nick end labeling, WGA: wheat germ agglutinin. Data presented as mean ± SD. Statistical analysis performed with two-way ANOVA

    Article Snippet: The tissue sections were dewaxed and rehydrated, followed by a 60-min incubation with WGA staining (2 ng/ml, VECTOR, RL-1002).

    Techniques: Over Expression, Staining, Expressing, Western Blot, Activity Assay, TUNEL Assay